Paediatric Pulmonology and Allergology

2007 April, Vol. X, No. 1 (3517-3523)

BCG-RELATED LYMPHADENITIS IN CHILDREN

Danutė Jadzevičienė¹, Rita Šopienė¹, Arūnas Valiulis², Povilas Venckus³

¹Šiauliai Regional TB and Lung Diseases Hospital, Šiauliai;

²Vilnius City University Hospital, Dept of Paediatric Pulmonology, Vilnius;

³Šiauliai City Hospital, Dept of Paediatric Surgery, Šiauliai

The aim of our retrospective survey was to determine incidence and treatment of BCG related lymphadenitis in Šiauliai region of Lithuania during the period from 2000 to 2005. We have analysed medical documentation of 17 children with BCG-related lymphadenitis admited for treatment to Šiauliai Regional TB and Lung Diseases Hospital, and of 23 children with BCG-related lymphadenitis admited for treatment to Šiauliai Hospital. Incidence of BCG-related lymphadenitis in Šiauliai region was 0.1–1.3 perc. (according to WHO data, worldwide incidence is 1–2 perc.). Overall condition of all patients was normal, no changes were reported in 2–6 months period of the observation. All patients had slight increase in the number of leucocytes and a lower haemoglobin. Few different strategies were found: surgery treatment for 11 patients, 5 of them have received antituberculous medicine (1H, 2HR , 6H , 2H) in the initial phase of the illness. It was found no protective effect of antituberculous medicines during initial phase of suppuration of BCG-related lymphadenitis. Six patients were observed with no treatment. Outcomes were good both in surgery and passive observation groups. We have concluded, that incidence of BCG-related lymphadenitis in Šiauliai region is low. Treatment with antituberculous medicine does not reduce the risk of suppuration. Surgical treatment can be applicable only in cases of suppurative lymphadenitis.

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